Dosing & Administration Guidelines

Dosing and Administration Guidelines for Medical Cannabis

At MOCA Health, we are committed to providing safe and effective cannabis-based treatments for our patients. When it comes to medical cannabis, dosing and administration are critical components of successful treatment. Medical cannabis products, including marijuana buds and cannabis oils, offer therapeutic benefits, but proper dosing is essential to maximize efficacy and minimize risks.

Here, we provide an overview of TGA-compliant dosing information, the importance of individualized dosing, and general guidelines for administering cannabis-based treatments.

TGA-Compliant Dosing for Marijuana Buds and Cannabis Oils

In Australia, the Therapeutic Goods Administration (TGA) regulates the use of medical cannabis, ensuring that products are safe and effective for patients. The TGA’s guidelines focus on safety, efficacy, and quality, but dosing varies based on the specific cannabis product being used, as well as the patient’s condition and individual needs.

For medical cannabis products such as marijuana buds and cannabis oils, there are no one-size-fits-all dosing recommendations. Dosage depends on factors such as the concentration of THC (tetrahydrocannabinol) and CBD (cannabidiol), the method of administration, and the patient’s response to treatment.

• Marijuana Buds: When using marijuana buds (also referred to as cannabis flowers), patients typically vaporize or smoke them, which results in faster onset of effects. The THC content in marijuana buds varies, so it is important to start with a low dose and gradually increase as needed. Patients should follow the advice of their prescribing doctor, who will recommend an initial dosage that may start low and increase depending on how the body reacts.

• Cannabis Oils: Cannabis oils provide a more controlled and longer-lasting form of treatment, as they are typically taken orally. The dosing for oils depends on the concentration of THC and CBD. For oils, TGA-compliant products generally specify the dosage per milliliter, allowing for precise and controlled dosing. Doctors will guide patients on the correct dosage, and this will depend on the condition being treated.

Starting Low and Going Slow

The key to safe and effective cannabis use is starting with a low dose and gradually increasing it as needed. This approach, often referred to as “start low, go slow”, helps minimize the risk of adverse effects while allowing the body to adjust to the medication.

According to research by Stith et al. (2019), this principle is particularly important when using cannabis for the treatment of chronic conditions or when starting cannabis treatment for the first time. The goal is to find the minimum effective dose — the lowest dose that provides therapeutic benefits with the fewest side effects.

Initial Dosing: For first-time users or those switching between products, doctors may recommend starting with a low dose of cannabis oil or marijuana buds, typically around 2.5 mg to 5 mg of THC. Patients should use the product as directed and wait for several hours (usually 4–6 hours) to assess the effects. This time frame is particularly important for oils, as they take longer to metabolize compared to smoking or vaporizing.

Gradual Increase: If the initial dose is well tolerated but does not provide sufficient symptom relief, the dose may be gradually increased. This should be done in small increments, typically every few days or as directed by the prescribing doctor. This approach ensures that patients can monitor how they feel with each increase and avoid side effects like dizziness or sedation, which can occur with higher doses of THC.

Importance of Individualized Dosing

Cannabis affects everyone differently due to a variety of factors, including genetics, metabolism, and the condition being treated. Individualized dosing is crucial to ensure that each patient receives the right amount of medicine for their unique needs. What works for one patient may not work for another.

The effectiveness of cannabis can also depend on body weight, age, and overall health. For example, patients who are new to cannabis may need a lower starting dose compared to experienced users, who may require a higher dose for therapeutic effects. Similarly, people with conditions like chronic pain may require higher doses than someone using cannabis for anxiety or insomnia.

It's essential for patients to work closely with their doctor to develop a treatment plan that meets their specific needs. Ongoing communication with healthcare providers allows adjustments to the dosage and product types based on the patient’s response to treatment.

Methods of Administration

Cannabis-based treatments can be administered in several different ways, each with its own considerations for dosing. The most common methods of cannabis administration are:

• Smoking and Vaporizing: Smoking or vaporizing cannabis buds provides rapid effects, with THC reaching the bloodstream almost immediately. However, because the effects are quick, they can be difficult to control. It is advised that patients start with a very small amount and monitor how they feel over the next 1–2 hours.

• Oils and Tinctures: Oral cannabis products such as oils and tinctures are more controlled in their dosing, but their onset can take longer (anywhere from 30 minutes to 2 hours). It is important for patients to follow dosing instructions carefully, as higher doses can cause unwanted side effects.

• Edibles: Edibles like cannabis-infused chocolates or gummies take longer to take effect but can provide long-lasting relief. Dosing with edibles should be started at a low amount (e.g., 5 mg of THC) to gauge tolerance.

Monitoring and Adjustments

Once the correct dose is established, patients should regularly monitor their symptoms and side effects. Keeping a journal of dosages, times of consumption, and effects is helpful for both patients and their healthcare providers. If side effects occur, such as dizziness, dry mouth, or fatigue, the dose may need to be adjusted.

Healthcare providers may also recommend periodic check-ins to adjust the dosage or explore alternative methods of administration. This collaborative approach ensures that the treatment plan remains effective and safe over time.

Conclusion

At MOCA Health, we prioritize patient safety and individualized care. By following TGA-compliant dosing guidelines and working closely with a medical professional, patients can use cannabis products effectively for a variety of conditions. Starting low and going slow allows patients to find the right dose and method for their specific needs while minimizing risks. Always consult with your healthcare provider before making any changes to your cannabis treatment plan.